Preparation-H Cream with Bio-Dyne (also known as LYCD - Live Yeast
Cell Derivative) is used for wrinkles because it works. No fancy
packaging, exotic smells, and sky high pricing.
No advertising either- it is a word of mouth
endorsement where people visiting our sister site http://www.CanadaPharmacy.com began
requesting Prep-H from Canada because the USA made cream did not
have the same results. It worked for Granny but once the Bio-Dyne
was removed it was just another hemorrhoid cream.
This chapter in Dr. Graedon's book was also
written due to consumer requests and questions. A PhD Pharmacist who
knows his research on what really works and what just masks the
symptoms. The People's Pharmacy Guide to
Home and Herbal Remedies 1999
Joe & Teresa Graedon PhD
Excerpt from p. 171 Testimonial Page
'Question: I was astonished when
my best friend told me that she used Preparation H on her face. She
said it helped smooth the wrinkles around her eyes.'
'Answer: Preparation H has been
used for lots of things besides hemorrhoids. We have heard of it
being employed for bed sores, itchy surgical scars, burns, dry
cracked finger, and yes, even wrinkles. The most familiar
store-bought hemorrhoid preparation is Preparation-H.'
'But it isn't what it used to be. For decades Prep
H contained two natural ingredients, live yeast cell derivative
(LYCD) and shark liver oil. No more.The Food and Drug Administration
reviewed the ingredients of hundreds of over the counter
medications. When they were done, a number of products were
reformulated, and many others simply disappeared. Preparation H was
one of those brands the FDA said had to be reformulated.'
'Forget the fact that millions of people loved it
and made it the best selling hemorrhoidal product on the market. We
used to make fun of shark liver oil and LYCD, but not anymore. We
discovered data that suggested LYCD accelerated wound healing.
People told us there was nothing better for their dry, cracked,
irritated skin or their hemorrhoids. We received countless
testimonials from folks who swore it was the only thing that
relieved the itching of their surgical scars. Many women even used
Prep H for wrinkles.'
'Now in the USA Prep-H contains an astringent
called phenylepherine instead of Bio-Dyne. We wish the FDA had not
meddled with a perfectly fine product. We have never been impressed
with the notion of using a vasoconstrictor on hemorrhoids, though
the FDA seems to think this makes sense. When phenylepherin wears
off it causes rebound dilation and congestion.' It really must work or no one would use it! No fancy
jar, advertising, or high prices. Just the medically proven healing
ingredient called Bio-Dyne. The legends that encouraged hundreds of
models and actresses to overcome their squeamishness and apply a
hemorrhoid cream to their most valuable feature - their face- came
from the experience of using Prep-H with Bio-Dyne.
buy anything at any price but have settled on Prep-H. They don't
really want the world to know they are using hemorrhoid cream on
their faces. It doesn't smell like a cosmetic and it is not packaged
in a jar worth $10. It has the reputation of being used for curing hemorrhoids. But it works and that is what really counts.
So why do those most concerned (some might even
say vain) about their appearances put Prep-H on their face and body?
The answer is that it works and you see the
results immediately. That is why make-up professionals recommend
their clients such as Conan O'Brien and Miss USA, use Canadian
The Science of Skin Healing with Bio-Dyne
now know that Bio-Dyne is biologically active on skin cells. There
are clinical studies from the Cincinnati Burn Unit and Oregon
University School of Medicine to show that Bio-Dyne speeds wound
healing in burns and post surgically. The active ingredient has even
been isolated as a protein fraction containing a mixture of several
peptides Fortunately no one has told the Canadian manufacturer of
Prep-H to remove its Bio-Dyne. You will see the ingredient on the
label as Yeast as a live cell derivative (Bio-Dyne: Skin Respiratory
Factor) 1%. That is in addition to the Shark Liver Oil at 3% Making
Bio-Dyne Live Yeast Cell extract is a sensitive and expensive
process which provides the skin respiratory factor in the purest
You may have heard of similar factors in top of
the line cosmetics such as La Prairie. The discussion we have had
applies to using Prep-H for hemorrhoids or as a skin cream. Use
Prep-H Ointment for dry skin, chapped hands, or hemorrhoids. Use the
Prep-H Cream for wrinkles and the Prep-H Cooling Gel for
hemorrhoids. The Scientists have studied Prep-H- read it here:
"Topical application of yeast extract accelerates the wound healing
of diabetic mice." Crowe MJ, McNeill RB, Schlemm DJ, Greenhalgh DG,
Keller SJ. Shriners Hospitals for Children-Cincinnati Burns
Alcoholic extracts of yeast have been used as the
active ingredient in medications under names such as "tissue or skin
respiratory factor," Biodyne (Sperti Drug Co, Cincinnati, Ohio--now
defunct), and live yeast cell derivative (LYCD). Beneficial clinical
results from the use of LYCD have been reported for the treatment of
burns, wounds, and hemorrhoids. The medicinal effects of LYCD have
recently been localized to a protein fraction containing a mixture
of several peptides. The effects of topical application of the
peptide mixture on wounds were examined in diabetic mice, an animal
model in which the healing process is disrupted and delayed.
Full-thickness wounds were created on the backs of diabetic (DB) and
non-diabetic (non-DB) mice. Half of the DB and non-DB mice were
treated with 0.05 mL of LYCD after wounding and for 4 successive
days. All other mice received vehicle. Wound areas were measured at
Day 0 and at 2-day intervals. Mice were sacrificed at 3, 7, 10, 21,
and 28 days post injury. Differences in the extent and quality of
healing appeared between DB mice receiving LYCD and DB mice
receiving vehicle by day 10 (P < .0001). By 24 days post injury,
DB mice receiving LYCD had achieved 100% wound closure, whereas DB
mice receiving vehicle had achieved only 31.4% wound closure.
Histologic examination of wounds reflected improved wound healing in
DB mice receiving LYCD as compared with those receiving vehicle. A
topically applied yeast extract peptide mixture significantly
attenuates wound closure and the degree of cellular reorganization
of full-thickness accessional wounds of DB mice.
PMID: 10188114 [PubMed - indexed for MEDLINE]
Peptides from live yeast cell derivative stimulate wound healing.
Bentley JP, Hunt TK, Weiss JB, Taylor CM, Hanson AN, Davies
GH, Halliday BJ.
Department of Biochemistry, Oregon Health Sciences
University School of Medicine, Portland 97201. Live yeast cell
derivative is an alcoholic extract from yeast (Saccharomyces
cerevisiae) that has previously been shown by three groups of
workers to stimulate wound healing. Live yeast cell derivative is a
complex mixture, and it was not known which of its many components
was responsible for the biological activity. This study describes
the separation and analysis of the major components, one of which is
a peptide fraction that stimulates wound healing. The fraction
consists of a mixture of peptides from 6000 to 17,000 d. It causes
angiogenesis in a chick embryo yolk sac membrane assay and in a
rabbit cornea assay, and it dramatically stimulates wound healing in
the "Schilling/Hunt" wire mesh cylinder model at concentrations
25-fold lower than those required for the intact live yeast cell
derivative. PMID: 1691911 [PubMed - indexed for MEDLINE]
Only in Canada eh! That's right, the
original product is available from Canada and can be ordered online.